Description

Hemoglobin Mississippi (CAS 113536-26-8) is a specific, naturally occurring variant of hemoglobin, a critical oxygen-transporting protein found in red blood cells. This compound is of significant value in biochemical research and diagnostic development for studying hemoglobinopathies and related blood disorders. It serves as an essential reference standard and raw material for researchers, clinical laboratories, and diagnostic manufacturers focused on hematology and genetic disease analysis. Its precise characterization is vital for advancing understanding in fields like molecular biology and clinical diagnostics.

Application

• Biochemical Research Standard: Used as a purified reference material for comparative studies of hemoglobin structure, function, and oxygen-binding kinetics.
• Diagnostic Kit Development: Serves as a key component in the formulation of controls and calibrators for clinical assays detecting hemoglobin variants.
• Hematology Studies: Employed in laboratory investigations into sickle cell disease, thalassemias, and other hemoglobinopathies to understand disease mechanisms.
• Pharmaceutical Research: Utilized in early-stage research for developing therapeutic agents targeting abnormal hemoglobin proteins.
• Educational & Training Material: Provides a specific example for teaching advanced concepts in protein chemistry, genetics, and clinical laboratory science.

Basic Information

Item	Detail
Product Name	Hemoglobin Mississippi
CAS No.	113536-26-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb Mississippi; Hemoglobin variant Mississippi; Hemoglobin α2β2 44(CD2) Ser→Arg; HBB: c.134 C>G; Hemoglobin α-chain variant; β-globin variant; Deoxyhemoglobin Mississippi (where applicable); Oxyhemoglobin Mississippi (where applicable)
EINECS	Contact for details

Quality Control

Our Hemoglobin Mississippi is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is characterized using advanced analytical techniques to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation. For short-term use, keep at 2-8°C and allow to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Lyophilized powder or specified solution
Identification (HPLC/MS)	Conforms to standard for Hemoglobin Mississippi
Purity (HPLC)	≥ 95% (or as specified per grade)
Protein Content (Biuret)	≥ 90% of total mass
Hemoglobin Form	Specified (e.g., Oxy, Deoxy, Met)
Solubility	Clear solution in specified buffer
Endotoxin	< 1.0 EU/mg (for research-grade)
Biological Activity	Evaluated by oxygen dissociation curve (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.