Description

Selenomethionine[75Se] is a radiolabeled analog of the essential amino acid methionine, where a selenium-75 radioisotope replaces the sulfur atom. This compound is critical for non-invasive metabolic tracing and imaging studies in biomedical research and diagnostic development. It is primarily utilized by pharmaceutical R&D teams, clinical research organizations, and academic institutions focused on oncology, neurology, and metabolic pathway analysis.

Application

• Radiotracer in Positron Emission Tomography (PET) Imaging: Used to study methionine uptake and protein synthesis rates in tumors and brain tissues.
• Biomedical Research: A vital tool for tracing selenomethionine incorporation into proteins and studying selenium metabolism in vivo.
• Oncology Studies: Enables the visualization and monitoring of cancer cell proliferation and treatment efficacy.
• Neurological Research: Facilitates the investigation of amino acid transport across the blood-brain barrier and related disorders.
• Diagnostic Agent Development: Serves as a key precursor in the research and development of novel radiopharmaceuticals.
• Metabolic Pathway Analysis: Used to elucidate specific biochemical pathways involving sulfur/selenium amino acids.

Basic Information

Product Name	Selenomethionine[75Se]
CAS No.	1187-56-0
Molecular Formula	C5H11NO2Se
Molecular Weight	196.11 g/mol (unlabeled base)
Synonyms	L-Selenomethionine[75Se]; (75Se)-Selenomethionine; Selenium-75 L-Selenomethionine; [75Se]SeMet; 75Se-Methionine; Radioactive Selenomethionine; 2-Amino-4-(methylseleno)butanoic acid[75Se]
EINECS	214-701-3 (for unlabeled L-Selenomethionine)

Quality Control

Every batch of Selenomethionine[75Se] is manufactured and tested under strict radiopharmaceutical-grade conditions to ensure high specific activity, radiochemical purity, and sterility where applicable. Our quality assurance protocol includes rigorous analytical testing. A comprehensive Certificate of Analysis (COA) detailing specific activity, radiochemical purity (by HPLC), radionuclidic purity, and other critical parameters is provided with each shipment to ensure traceability and compliance with research standards.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being strictly light-sensitive and easily oxidized, this material must be stored under an inert atmosphere (e.g., argon or nitrogen) at recommended cold chain temperatures (typically -20°C or as specified on the COA). Store in accordance with all local and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (HPLC/Radio-TLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 95%
Specific Activity	Contact for details
Radionuclidic Purity	≥ 99%
Chemical Purity (HPLC)	Contact for details
pH	Specified range (e.g., 5.0 - 7.5)
Sterility Test (if sterile filtered)	Sterile
Bacterial Endotoxins (LAL)	< 175 EU/mL (for injectable grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.