Description

Taicatoxin CAS NO 112154-17-3 is a potent, high-purity peptide toxin isolated from the venom of the Australian taipan snake (*Oxyuranus scutellatus*). This compound is of significant value in advanced biochemical and pharmacological research due to its specific and high-affinity blockade of voltage-gated calcium channels. It is primarily required by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers for use in neurophysiological studies, ion channel characterization, and the development of novel therapeutic agents.

Application

• Neuroscience Research: A critical tool for studying the function and modulation of L-type calcium channels in neuronal and cardiac tissues.
• Pharmacological Assay Development: Used as a reference standard in high-throughput screening (HTS) assays to identify new calcium channel blockers or modulators.
• Ion Channel Characterization: Essential for electrophysiology experiments (e.g., patch-clamp) to probe channel kinetics and pharmacology.
• Toxicology Studies: Employed in mechanistic studies of snake envenomation and the development of targeted antivenoms or treatments.
• Biochemical Reagent: Serves as a selective ligand in receptor binding studies and affinity purification protocols.
• Diagnostic Manufacturing: Potential use as a component in specialized diagnostic kits for channelopathy research.

Basic Information

Item	Details
Product Name	Taicatoxin
CAS No.	112154-17-3
Molecular Formula	C254H402N74O75S8 (Approx., for main component)
Molecular Weight	~5560 Da (Approx.)
Synonyms	Taicatoxin; Taipan Toxin; Calcium Channel Blocker Toxin (Taipan); Oxyuranus scutellatus Toxin; L-type Calcium Channel Blocker; TCX; CAS 112154-17-3; ω-Taipan Toxin
EINECS	Contact for details

Quality Control

Our Taicatoxin is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing purity, bioactivity (where applicable), and safety data. Our quality system supports research requiring materials traceable to reliable standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted to avoid repeated freeze-thaw cycles and stored at -70°C or below. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under anhydrous conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	Contact for details
Endotoxin Level	< 1.0 EU/mg
Moisture Content (KF)	< 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.