Description

Uridine (15N2, 98%) is a stable isotope-labeled nucleoside, specifically enriched with nitrogen-15 at two positions, with a minimum chemical purity of 98%. This high isotopic enrichment and chemical purity make it an essential internal standard and tracer for advanced quantitative analysis in life science research. It is primarily used by researchers and manufacturers in the fields of metabolomics, pharmaceutical development, and diagnostic assay production who require precise, interference-free measurement of nucleotide metabolism and RNA synthesis pathways.

Application

• Quantitative Mass Spectrometry (MS) & NMR: Serves as a critical internal standard for the accurate quantification of endogenous uridine and related metabolites in complex biological samples like plasma, urine, and cell lysates.
• Metabolic Flux Analysis: Used as a stable isotopic tracer to study the dynamics of the pyrimidine salvage pathway, nucleotide synthesis, and RNA turnover in cell culture and in vivo models.
• Pharmaceutical R&D: Employed in the development and validation of bioanalytical methods for novel nucleoside-based therapeutics, including antivirals and oncology drugs.
• Clinical Diagnostics: Facilitates the development of high-precision LC-MS/MS assays for diagnosing inborn errors of metabolism related to nucleotide synthesis disorders.
• Biochemical Research: A key reagent for enzymatic studies, investigating the kinetics and mechanisms of kinases, phosphorylases, and other nucleotide-interacting enzymes.

Basic Information

Product Name	Uridine (15N2, 98%)
CAS No.	92487-68-8
Molecular Formula	C9H12N215N2O6
Molecular Weight	Contact for details
Synonyms	1-β-D-Ribofuranosyluracil-15N2; Uridine-15N2; [15N2]-Uridine; 15N Labeled Uridine; Nitrogen-15 Uridine; Stable Isotope Labeled Uridine; Uridine (double nitrogen-15 labeled); Uridine-1,3-15N2
EINECS	Contact for details

Quality Control

Every batch of Uridine (15N2, 98%) is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards for isotopic and chemical purity. Certificates of Analysis (COA) are available upon request, providing detailed results for isotopic enrichment (Atom % 15N), chemical purity (HPLC), and identity confirmation (NMR/MS).

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR/MS)	Conforms to labeled structure
Isotopic Enrichment (Atom % 15N)	≥98% (min)
Chemical Purity (HPLC)	≥98% (min)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.