Description

3-o-(14C-Methyl)-D-Glucose is a radiolabeled glucose derivative, specifically a methylated glucose molecule where the methyl group contains the carbon-14 isotope. This compound is a critical tool for metabolic pathway tracing and pharmacokinetic studies, offering researchers a precise method to track glucose utilization and modification in biological systems. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on diabetes research, cancer metabolism, and drug development.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study glucose uptake, glycolysis, and the pentose phosphate pathway in cell cultures and animal models.
• Drug Metabolism and Pharmacokinetics (DMPK): Essential for investigating the absorption, distribution, metabolism, and excretion (ADME) of new therapeutic compounds that interact with glucose pathways.
• Biochemical Research: Serves as a substrate in enzymatic assays to study the activity of glycosyltransferases and other carbohydrate-modifying enzymes.
• Oncology Research: Applied in studies of the Warburg effect and altered energy metabolism in cancer cells.
• Diagnostic Agent Development: A potential precursor in the development of novel Positron Emission Tomography (PET) imaging agents, though typically requiring different isotopes like carbon-11 or fluorine-18.

Basic Information

Product Name	3-o-(14C-Methyl)-D-Glucose
CAS No.	92304-15-9
Molecular Formula	C₇H₁₄O₆ (with ¹⁴C label)
Molecular Weight	~194.18 g/mol (exact mass depends on ¹⁴C position)
Synonyms	3-O-Methyl-D-glucose-¹⁴C; D-Glucose, 3-O-methyl-, (methyl-¹⁴C)-; 3-O-Methyl-D-[methyl-¹⁴C]glucose; 3-OMG-¹⁴C; Methyl-¹⁴C labeled 3-O-methyl-D-glucose; 3-O-(¹⁴C-Methyl)glucose; Radiolabeled 3-O-methylglucose
EINECS	Contact for details

Quality Control

Our radiolabeled compounds are produced and tested under strict quality systems. Each batch of 3-o-(14C-Methyl)-D-Glucose is characterized for radiochemical purity (typically >98% by HPLC), specific activity, and chemical purity. Certificates of Analysis (COA) detailing HPLC chromatograms, NMR data, and analytical results are provided to ensure traceability and compliance with research standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer for radioactive materials. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation. Store in accordance with all local and national regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid or solution
Identification (HPLC, NMR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Specific Activity	50-60 mCi/mmol (Contact for specific batch data)
Chemical Purity (HPLC)	≥ 95%
Solvent (if supplied as solution)	Ethanol:Water or other specified solvent
Concentration (if supplied as solution)	1.0 mCi/mL ± 10%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.