Description

Bemarinone is a synthetic organic compound with significant pharmacological activity, primarily recognized as a cardiotonic agent. This high-purity intermediate is critical for pharmaceutical research and development, offering reliable quality for synthesizing active pharmaceutical ingredients (APIs). It is essential for researchers and manufacturers in the pharmaceutical and life sciences industries focused on cardiovascular drug discovery and development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of cardiotonic and inotropic drugs.
• Cardiovascular Research: Used as a reference standard and active compound in preclinical studies for heart failure treatments.
• API Development: Serves as a crucial precursor in the manufacturing process of final active pharmaceutical ingredients.
• Biochemical Research: Employed in studies investigating phosphodiesterase III (PDE III) inhibition and related cellular mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Utilized in analytical laboratories for method development, validation, and quality control testing.

Basic Information

Product Name	Bemarinone
CAS No.	92210-43-0
Molecular Formula	C₁₉H₂₀N₂O₃
Molecular Weight	324.38 g/mol
Synonyms	1,2,3,4-Tetrahydro-6-[4-(pyridin-4-yl)butyl]-2(1H)-quinazolinone; 6-[4-(4-Pyridinyl)butyl]-1,2,3,4-tetrahydro-2-quinazolinone; OPC-8212; BMY-43351; Cardiotonic agent OPC-8212
EINECS	Contact for details

Quality Control

Our Bemarinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for assay and related substances, to meet rigorous pharmaceutical-grade standards. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.