Description

Pimobendan is a potent and selective phosphodiesterase III (PDE III) inhibitor with calcium-sensitizing properties. This dual mechanism of action makes it a critical active pharmaceutical ingredient (API) for the treatment of cardiovascular conditions in veterinary medicine. It is primarily utilized by pharmaceutical manufacturers and research institutions developing specialized veterinary cardiology products. The compound is supplied under the identifier CAS No. 74150-27-9.

Application

• Veterinary Pharmaceutical API: Primary use as the active ingredient in chewable tablets and oral suspensions for the management of congestive heart failure (CHF) in dogs, specifically for the treatment of myxomatous mitral valve disease (MMVD) and dilated cardiomyopathy (DCM).
• Clinical Research & Development: Serves as a key reference standard and building block in preclinical and clinical studies for novel inotropic agents.
• Veterinary Generic Drug Formulation: Used by generic drug manufacturers to produce bioequivalent versions of established pimobendan-based therapies.
• Pharmacology Studies: Employed in academic and industrial research to investigate calcium sensitization and PDE inhibition pathways in cardiac muscle.

Basic Information

Product Name	Pimobendan
CAS No.	74150-27-9
Molecular Formula	C19H18N4O2
Molecular Weight	334.37 g/mol
Synonyms	4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)-pyridazinone; UD-CG 212 BS; Acardi; Vetmedin; (+)-Pimobendan; (R)-Pimobendan
EINECS	Contact for details

Quality Control

Our Pimobendan is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay, enantiomeric purity, and impurity profiles. We support compliance with cGMP and relevant veterinary pharmacopoeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (R)-Isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual unknown impurity ≤ 0.10% Total impurities ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.