Description

2-(4-Fluoro-Benzoylamino)-3-Methyl-Butyric Acid is a high-purity, non-natural amino acid derivative featuring a fluorinated aromatic moiety. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the introduction of specific steric and electronic properties into target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for introducing fluorinated pharmacophores.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to construct modified peptide backbones and non-peptide structures that mimic biological activity.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, or plant growth regulators with enhanced properties.
• Material Science: Potential monomer or precursor for specialty polymers and advanced materials requiring specific functional groups.
• Chemical Biology & Proteomics: Employed in the synthesis of probes, inhibitors, or labeled compounds for studying enzyme mechanisms and protein interactions.
• Academic & Industrial R&D: A versatile reagent for methodological studies in asymmetric synthesis and fluorine chemistry.

Basic Information

Product Name	2-(4-Fluoro-Benzoylamino)-3-Methyl-Butyric Acid
CAS No.	92054-21-2
Molecular Formula	C13H16FNO3
Molecular Weight	253.27 g/mol
Synonyms	N-(4-Fluorobenzoyl)-L-valine; (S)-2-((4-Fluorobenzoyl)amino)-3-methylbutanoic acid; 2-[(4-Fluorobenzoyl)amino]-3-methylbutyric acid; L-Valine, N-(4-fluorobenzoyl)-; 4-Fluoro-N-[(2S)-1-hydroxy-3-methyl-1-oxobutan-2-yl]benzamide; 92054-21-2; 2-(4-Fluorobenzamido)-3-methylbutanoic acid
EINECS	Contact for details

Quality Control

Our production of 2-(4-Fluoro-Benzoylamino)-3-Methyl-Butyric Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.