Description

Di-(n-Glycolylneuraminic Acid)Ganglioside Gd1B is a complex, glycosphingolipid ganglioside containing two N-glycolylneuraminic acid (Neu5Gc) residues. This compound is a critical research-grade biochemical for studying cell membrane structure, neural development, and specific receptor-ligand interactions. It serves as an essential standard and reagent in advanced biomedical research, particularly in neuroscience, immunology, and oncology. Researchers and manufacturers in the pharmaceutical and diagnostic sectors rely on its high purity for assay development and mechanistic studies.

Application

• Biomedical Research Standard: Used as a high-purity reference standard in analytical methods like HPLC and mass spectrometry for ganglioside quantification and characterization.
• Neuroscience Studies: Essential for investigating the role of gangliosides in neuronal cell adhesion, signal transduction, and the pathogenesis of neurological disorders.
• Immunology and Cancer Research: Applied in studies exploring ganglioside expression on cell surfaces, their function as antigens, and their involvement in tumor progression and immune response modulation.
• Diagnostic Reagent Development: Utilized in the development and calibration of diagnostic kits and assays targeting specific ganglioside biomarkers.
• Membrane Biology: Serves as a tool to study lipid raft composition, membrane fluidity, and the behavior of glycosphingolipids in cellular membranes.
• Glycobiology Research: A key substrate for enzymatic studies and for understanding the biosynthesis and catabolism of complex ganglioside pathways.

Basic Information

Item	Details
Product Name	Di-(n-Glycolylneuraminic Acid)Ganglioside Gd1B
CAS No.	91594-08-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ganglioside GD1b (Neu5Gc); GD1b Ganglioside (d18:1/18:0, Neu5Gc); II3(Neu5Gc)2-Gg4Cer; Disialylganglioside GD1b (N-Glycolyl); Di-N-glycolyl-GD1b; Neu5Gc-GD1b; GD1b with N-Glycolylneuraminic Acid; Bovine Brain Ganglioside GD1b (Neu5Gc variant)
EINECS	Contact for details

Quality Control

Every batch of Di-(n-Glycolylneuraminic Acid)Ganglioside Gd1B is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency for research applications. Our quality assurance includes comprehensive analytical testing via methods such as HPLC and TLC. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/TLC)	Conforms to reference standard
Assay (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in chloroform/methanol mixtures, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.