Description

3-(tert-Butyldimethylsilyloxy)Glutaric Anhydride is a high-value, protected glutaric acid derivative, serving as a critical chiral building block and versatile synthon in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of functionalized glutarate moieties while offering orthogonal protection strategies for sensitive functional groups. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing complex molecules like active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral drugs, prodrugs, and complex bioactive molecules.
• Peptide & Protein Modification: Used for the site-specific modification of amino acids, enabling the study of protein structure and function.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for the production of specialty polyesters and biodegradable polymers with tailored properties.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a scaffold for synthesizing novel chiral ligands used in asymmetric catalysis.
• Material Science Research: Employed in the development of advanced organic materials and liquid crystals.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	3-(tert-Butyldimethylsilyloxy)Glutaric Anhydride
CAS No.	91424-40-7
Molecular Formula	C11H20O4Si
Molecular Weight	244.36 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]glutaric anhydride; 3-(TBDMSO)Glutaric Anhydride; 3-(tert-Butyldimethylsiloxy)glutaric anhydride; Glutaric Anhydride, 3-(tert-butyldimethylsilyloxy)-; 3-Hydroxyglutaric Anhydride TBDMS Ether; 3-(Tert-butyldimethylsilyloxy)pentanedioic anhydride
EINECS	Contact for details

Quality Control

Our 3-(tert-Butyldimethylsilyloxy)Glutaric Anhydride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.