Description

5-(N,N-Dimethylsulfamoyl)-2-fluorobenzoic acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in the strategic combination of the sulfonamide and fluorine functional groups, which are essential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, where the fluorine atom and sulfonamide group enhance bioactivity and environmental stability.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex molecular architectures via coupling reactions, amide bond formation, and further functional group transformations.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique surface properties or for advanced material applications.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor-ligand interactions.

Basic Information

Product Name	5-(N,N-Dimethylsulfamoyl)-2-fluorobenzoic Acid
CAS No.	91103-94-5
Molecular Formula	C9H10FNO4S
Molecular Weight	247.25 g/mol
Synonyms	2-Fluoro-5-(N,N-dimethylsulfamoyl)benzoic acid; 5-(Dimethylsulfamoyl)-2-fluorobenzoic acid; 2-Fluoro-5-[(dimethylamino)sulfonyl]benzoic acid; Benzoic acid, 2-fluoro-5-[(dimethylamino)sulfonyl]-; 91103-94-5; 5-Dimethylsulfamoyl-2-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 5-(N,N-Dimethylsulfamoyl)-2-fluorobenzoic acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.