Description

(n-Crotonyl)-(4S)-Isopropyl-2-Oxazolidinone CAS NO 90719-29-2 is a high-purity chiral auxiliary and building block widely used in asymmetric synthesis. Its value lies in enabling the stereoselective construction of complex molecules, which is critical for developing pharmaceuticals and advanced materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral reagents.

Application

• Asymmetric Synthesis: As a chiral auxiliary for the stereocontrolled formation of carbon-carbon and carbon-heteroatom bonds.
• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Development: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and catalysis research.
• Peptidomimetics & Bioconjugates: Facilitates the introduction of crotonyl groups and other functionalities into peptide backbones and biomolecules.
• Material Science: Potential monomer or precursor for creating chiral polymers and advanced functional materials.

Basic Information

Product Name	(n-Crotonyl)-(4S)-Isopropyl-2-Oxazolidinone
CAS No.	90719-29-2
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	(S)-4-Isopropyl-3-(2-butenoyl)-2-oxazolidinone; (S)-3-Crotonyl-4-isopropyl-2-oxazolidinone; (4S)-3-(2-Butenoyl)-4-(1-methylethyl)-2-oxazolidinone; (S)-N-Crotonyl-4-isopropyl-2-oxazolidinone; Evans Chiral Auxiliary Derivative; (S)-4-iPr-3-Crotonyl-oxazolidinone; (S)-3-(Crotonoyl)-4-isopropyloxazolidin-2-one
EINECS	Contact for details

Quality Control

Our (n-Crotonyl)-(4S)-Isopropyl-2-Oxazolidinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by NMR, HPLC, and optical rotation analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.