Description

(3S,4S)-Pyrrolidine-3,4-Diol is a high-purity chiral diol derivative of pyrrolidine, serving as a critical building block in asymmetric synthesis. Its rigid, functionalized structure makes it a valuable scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of glycosidase inhibitors, antiviral agents, and other bioactive molecules.
• Asymmetric Catalyst Ligand: Used to synthesize chiral ligands for metal-catalyzed reactions, enabling high enantioselectivity.
• Organic Synthesis Building Block: Employed in the construction of natural products, alkaloids, and complex heterocyclic compounds.
• Agrochemical Research: Serves as a precursor for developing novel chiral pesticides and herbicides with improved efficacy.
• Chemical Biology Probe: Utilized in the design of molecular probes to study enzyme mechanisms and carbohydrate recognition.

Basic Information

Item	Details
Product Name	(3S,4S)-Pyrrolidine-3,4-Diol
CAS No.	90481-32-6
Molecular Formula	C4H9NO2
Molecular Weight	103.12 g/mol
Synonyms	(3S,4S)-3,4-Dihydroxypyrrolidine; (3S,4S)-3,4-Pyrrolidinediol; (3S,4S)-1-Azaspiro[3.3]heptane-6,7-diol (tautomer); (3S,4S)-3,4-Dihydroxyazetidine (homolog); L-3,4-Dihydroxypyrrolidine; (3S-cis)-3,4-Dihydroxypyrrolidine; cis-3,4-Dihydroxypyrrolidine
EINECS	Contact for details

Quality Control

Our (3S,4S)-Pyrrolidine-3,4-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.