Description

(1S,2S,5S)-Ethyl [(2-Hydroxypinan-3-Ylene)Amino]Acetate is a high-purity, chiral intermediate of significant importance in asymmetric synthesis. Its value lies in its rigid pinane-based structure, which serves as a key building block for constructing complex molecules with precise stereochemistry. This compound is essential for research and production in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced catalysts.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel therapeutic agents, including antiviral and central nervous system (CNS) drugs.
• Asymmetric Catalyst Ligand Precursor: Used to develop and manufacture specialized ligands for metal-catalyzed reactions requiring high enantioselectivity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances where stereochemical control is paramount.
• Academic & Industrial R&D: Serves as a valuable reference standard and starting material for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(1S,2S,5S)-Ethyl [(2-Hydroxypinan-3-Ylene)Amino]Acetate
CAS No.	90473-00-0
Molecular Formula	C₁₄H₂₃NO₃
Molecular Weight	253.34 g/mol
Synonyms	Ethyl (1S,2S,5S)-2-hydroxy-3-pinanamineacetate; (-)-Ethyl [(2-Hydroxypinan-3-Ylene)Amino]Acetate; (1S,2S,5S)-2-Hydroxy-3-pinanamineacetic acid ethyl ester; Pinane amino acetate derivative; Chiral pinane derivative; (1S,2S,5S)-HPAE; AS-1 (common research code).
EINECS	Contact for details

Quality Control

Our (1S,2S,5S)-Ethyl [(2-Hydroxypinan-3-Ylene)Amino]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with full traceability are provided to guarantee compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.