Description

4-(2-Fluoro-Phenyl)-4-Oxo-Butyric Acid is a versatile fluorinated aromatic keto acid building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where the fluorine atom and reactive carbonyl groups enable precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine moiety enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on fluorination reactions and the study of fluorine's effects on molecular properties.
• Custom Synthesis & Contract Manufacturing: A high-value building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-(2-Fluoro-Phenyl)-4-Oxo-Butyric Acid
CAS No.	90429-80-4
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	4-Oxo-4-(2-fluorophenyl)butanoic acid; 2-Fluoro-γ-oxobenzenebutanoic acid; 4-(2-Fluorobenzoyl)butyric acid; 4-(2-Fluorophenyl)-4-oxobutanoic acid; γ-Oxo-2-fluorobenzenebutanoic acid; Butanoic acid, 4-oxo-4-(2-fluorophenyl)-; 90429-80-4; 4-(2-Fluorophenyl)-4-oxobutyric acid
EINECS	Contact for details

Quality Control

Our 4-(2-Fluoro-Phenyl)-4-Oxo-Butyric Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed when not in use to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.