Description

Darenzepine CAS NO 90274-22-9 is a selective muscarinic M1 receptor antagonist, a compound of significant interest in pharmacological research and development. Its primary value lies in its potential for studying cholinergic pathways and developing targeted therapeutic agents for central nervous system disorders. This high-purity compound is essential for researchers and pharmaceutical developers in the fields of neuropharmacology, drug discovery, and preclinical studies.

Application

• Pharmacological Research: Used as a selective tool compound for investigating the role and function of muscarinic M1 receptors in vitro and in vivo.
• Drug Discovery & Development: Serves as a reference standard and a key intermediate in the synthesis and screening of novel CNS-active pharmaceutical candidates.
• Neuroscience Studies: Applied in academic and industrial research to explore cholinergic mechanisms related to cognitive function, memory, and neurological conditions.
• Biochemical Assay Development: Utilized as a critical reagent in developing and validating high-throughput screening assays for receptor binding and functional activity.
• Preclinical Toxicology & Safety Pharmacology: Employed in studies to understand the safety profile and metabolic pathways of related anticholinergic compounds.

Basic Information

Product Name	Darenzepine
CAS No.	90274-22-9
Molecular Formula	C₂₀H₂₃N₃O₃
Molecular Weight	353.42 g/mol
Synonyms	Darenzepine; (-)-Darenzepine; (S)-Darenzepine; (S)-(-)-Darenzepine; 11-[[(2S)-1-Methyl-2-pyrrolidinyl]methyl]-5,6-dihydro-6-oxodibenz[b,e]oxepin; L-689,660; L 689660; L689660
EINECS	Contact for details

Quality Control

Our Darenzepine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.