Description

Hemoglobin Koln is a stable variant of hemoglobin, a critical oxygen-transporting protein found in red blood cells. This specific variant is of significant interest for biochemical research and diagnostic development due to its altered oxygen-binding properties. It serves as an essential reference material and reagent for researchers and manufacturers in the life sciences, clinical diagnostics, and pharmaceutical sectors, particularly for studies in hematology and oxygen transport physiology.

Application

• Biochemical Research Standard: Used as a reference standard in studies of hemoglobin structure, function, and oxygen affinity.
• Diagnostic Reagent Manufacturing: A key component in the production of calibrators and controls for clinical blood gas and hemoglobin analysis systems.
• Hematology Studies: Employed in laboratory investigations of hemoglobinopathies and other blood disorders to understand variant behavior.
• Pharmaceutical Development: Utilized in research for developing blood substitutes and oxygen-therapeutic agents.
• Educational & Training Material: Serves as a high-purity specimen for academic teaching and laboratory training in biochemistry and medical technology.
• Quality Control in Diagnostics: Acts as a critical material for verifying the performance and accuracy of hemoglobin electrophoresis and chromatography equipment.

Basic Information

Product Name	Hemoglobin Koln
CAS No.	9035-00-1
Molecular Formula	Contact for details
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb Koln; Hemoglobin Köln; Hemoglobin variant Koln; Unstable Hemoglobin Koln; HbCO; Oxyhemoglobin Koln; Methemoglobin Koln; Deoxyhemoglobin Koln
EINECS	Contact for details

Quality Control

Our Hemoglobin Koln is produced and handled under strict quality protocols. Each batch is characterized to ensure identity, purity, and functional consistency suitable for research and in-vitro diagnostic use. While not for human therapeutic administration, it is manufactured with a focus on reproducibility and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, spectral properties, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. Store in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR / UV-Vis)	Conforms to standard
Purity (HPLC / Electrophoresis)	≥ 95% (Hb Koln variant)
Protein Content (Biuret / BCA)	Reported on COA
Methemoglobin Content	< 5%
Oxygen Binding Capacity	Reported on COA
Solubility	Clear solution in buffer
Endotoxin	< 1.0 EU/mg (where specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.