Description

Hemoglobin J Cape Town is a naturally occurring variant of human hemoglobin, characterized by a specific amino acid substitution in the β-globin chain. This compound is of significant value in biochemical research and diagnostic development, serving as a critical reference material for studying hemoglobinopathies and oxygen transport mechanisms. It is primarily utilized by research institutions, clinical diagnostic laboratories, and pharmaceutical companies engaged in hematology and blood substitute development. The product is supplied as a high-purity biochemical reagent to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a standard or model protein in studies of hemoglobin structure, function, and stability.
• Clinical Diagnostics: Serves as a control or calibrator in diagnostic assays for detecting and characterizing rare hemoglobin variants.
• Hematology Studies: Essential for investigating the pathophysiology of hemoglobin J Cape Town and related blood disorders.
• Pharmaceutical Development: Acts as a reference compound in the research and quality control of potential blood-based therapeutics or oxygen carriers.
• Educational Purposes: Utilized in advanced university and medical school laboratories for teaching protein chemistry and molecular biology.

Basic Information

Product Name	Hemoglobin J Cape Town
CAS No.	9034-88-2
Molecular Formula	Contact for details
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb J Cape Town; Hemoglobin variant J-Cape Town; α-2A β-2 82 Lys->Asn; HBB: c.248A>C; Hemoglobin J (Cape Town); Oxyhemoglobin J Cape Town; Deoxyhemoglobin J Cape Town; Methemoglobin J Cape Town
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized for identity, purity, and functional integrity using advanced analytical techniques. Certificates of Analysis (COA) detailing specific test results, including spectral analysis and electrophoretic mobility, are available upon request. We adhere to stringent in-house quality protocols suitable for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For extended storage, consider lyophilized forms or storage under inert atmosphere.

Specification

Item	Specification
Appearance	Dark red to brown lyophilized powder or solution
Identification (IR / UV-Vis)	Conforms to standard for Hemoglobin J Cape Town
Purity (HPLC / Electrophoresis)	≥ 95% (by area)
Protein Content (Biuret / BCA)	≥ 90%
Methemoglobin Content	≤ 5%
Solubility	Clear solution in buffer (e.g., phosphate buffer saline)
Biological Activity (O2 Binding)	Retained (by spectrophotometric assay)
Endotoxin	< 1.0 EU/mg (where specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.