Description

Hemoglobin G Coushatta CAS NO 9034-70-2 is a specific variant of hemoglobin, the essential oxygen-transporting metalloprotein found in red blood cells. This product is of significant value for biochemical research and diagnostic development, offering a purified and characterized reference material. It is primarily needed by research institutions, diagnostic manufacturers, and biotechnology companies engaged in hematology studies, hemoglobinopathy research, and the calibration of clinical analyzers.

Application

• Biochemical Research Standard: Serves as a critical reference standard in studies of hemoglobin structure, function, and genetic variants.
• Diagnostic Kit Development: Used in the formulation and quality control of diagnostic assays and kits designed to detect and quantify abnormal hemoglobins.
• Clinical Analyzer Calibration: Essential for calibrating and validating instruments in clinical laboratories to ensure accurate hemoglobin analysis.
• Hematology Studies: Provides a controlled substrate for investigating oxygen-binding kinetics, stability, and interactions of hemoglobin variants.
• Pharmaceutical Research: Potential use in foundational research for blood substitute technologies and therapeutic oxygen carriers.
• Educational Reference: Employed in academic settings for advanced teaching and demonstration of protein chemistry and molecular biology principles.

Basic Information

Product Name	Hemoglobin G Coushatta
CAS No.	9034-70-2
Molecular Formula	C2952H4664N812O832S8Fe4 (Hemoglobin tetramer, approximate)
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb G-Coushatta; Hemoglobin G-Philadelphia; Hemoglobin α268(E17)Asn→Lysβ2; Hemoglobin variant G; HBB: c.206C>A; Deoxyhemoglobin G Coushatta (reduced form); Oxyhemoglobin G Coushatta (oxygenated form); Methemoglobin G Coushatta (oxidized form)
EINECS	Contact for details

Quality Control

Our Hemoglobin G Coushatta is produced and handled under stringent conditions to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes rigorous analytical testing, including purity assessment by HPLC, spectral analysis for characteristic Soret band absorption, and verification of the variant identity. A comprehensive Certificate of Analysis (COA) detailing purity, concentration, and spectral properties is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. Store away from strong oxidizing or reducing agents.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR / UV-Vis)	Conforms to standard for Hemoglobin G Coushatta
Purity (HPLC)	≥ 95% (by area)
Assay (Spectrophotometric)	90% - 110% of stated concentration
Absorbance Ratio (A540/A280)	Within specified range
Moisture Content (Karl Fischer)	≤ 5.0% (for lyophilized powder)
Biological Activity (O2 binding)	Contact for details
Endotoxin	< 1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.