Description

Exophthalmos Producing Substance is a specialized biochemical agent of significant interest in endocrinology and biomedical research. This compound is crucial for studying thyroid-related disorders and the mechanisms underlying Graves' ophthalmopathy. It serves as an essential research tool for pharmaceutical developers, academic institutions, and diagnostic laboratories focused on autoimmune diseases and hormone regulation.

Application

• Biomedical Research: Fundamental studies on the pathogenesis of thyroid eye disease (Graves' ophthalmopathy).
• Pharmaceutical Development: Screening and validation of potential therapeutic agents targeting autoimmune orbital inflammation.
• Diagnostic Assay Development: Used as a reference standard or antigen in the development of immunoassays for detecting specific autoantibodies.
• Academic & Clinical Studies: Investigating the molecular pathways connecting thyroid-stimulating hormone receptors and orbital fibroblast activation.
• Target Validation: A key reagent for confirming biological targets in drug discovery pipelines for endocrine disorders.

Basic Information

Product Name	Exophthalmos Producing Substance
CAS No.	9013-46-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	EPS; Exophthalmos-producing factor; Thyroid-associated ophthalmopathy factor; Graves' ophthalmopathy factor; Orbital autoantigen; Thyroid eye disease factor; Immunoglobulin G (IgG) fraction (related); Autoimmune orbital antigen
EINECS	Contact for details

Quality Control

Our Exophthalmos Producing Substance is produced under stringent conditions to ensure batch-to-batch consistency and biological activity. Quality is verified through a series of analytical and biological assays relevant to its research application. Certificates of Analysis (COA) detailing purity, activity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Handle under controlled conditions to maintain biological integrity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Bioassay/Immunoassay)	Conforms
Purity (SDS-PAGE/HPLC)	>95% (or as per grade)
Biological Activity	Confirmed by cell-based assay
Endotoxin Level	<1.0 EU/mg (for in vitro use)
Protein Concentration	Specified on label
Solubility	Specified buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.