Description

Tributylphosphine CAS NO 998-40-3 is a versatile organophosphorus compound characterized by its strong nucleophilic and reducing properties. This tertiary phosphine is a critical reagent in organic synthesis, valued for its ability to facilitate a wide range of chemical transformations under mild conditions. It is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors seeking efficient catalysts and ligands for cross-coupling and other key reactions.

Application

• Pharmaceutical Intermediates: Acts as a crucial ligand and catalyst in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) for constructing complex drug molecules.
• Agrochemical Synthesis: Employed in the production of advanced pesticides and herbicides, where it serves as a reducing agent and catalyst.
• Polymer & Material Science: Used as a catalyst in the synthesis of specialty polymers, including polyurethanes and epoxy resins, and as a surface modifier for nanomaterials.
• Fine Chemical Manufacturing: Functions as a powerful nucleophile and reducing agent in the synthesis of flavors, fragrances, and other high-value fine chemicals.
• Hydroformylation Catalyst: Serves as a ligand in transition metal complexes for hydroformylation reactions, converting alkenes into aldehydes.
• Chemical Research & Development: A staple reagent in academic and industrial R&D for exploring new synthetic methodologies and developing novel organometallic complexes.

Basic Information

Product Name	Tributylphosphine
CAS No.	998-40-3
Molecular Formula	C12H27P
Molecular Weight	202.32 g/mol
Synonyms	Tributylphosphane; Tri-n-butylphosphine; TBP; Phosphorous tributyl; n-Tributylphosphine; Butylphosphine, tributyl-; Tributyl phosphine; 1-Butanephosphine, 1,1,1-tributyl-
EINECS	213-651-2

Quality Control

Our Tributylphosphine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area, away from heat, ignition sources, and oxidizing agents. Recommended long-term storage temperature is 2-8°C. Due to its pyrophoric nature in air, containers must be kept sealed and handled with appropriate precautions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Phosphine Oxide Content	≤ 2.0%
Density (at 20°C)	0.80 - 0.82 g/mL
Refractive Index (n20D)	1.455 - 1.465

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.