Description

(S)-(-)-1-Ethyl-2-Pyrrolidinecarboxylic Acid Ethyl Ester is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound matters because it serves as a crucial building block for the production of advanced pharmaceutical active ingredients and fine chemicals, enabling the creation of enantiomerically pure products. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysis, enabling stereoselective transformations.
• Agrochemical Synthesis: Employed in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	(S)-(-)-1-Ethyl-2-Pyrrolidinecarboxylic Acid Ethyl Ester
CAS No.	938-54-5
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(S)-1-Ethyl-2-pyrrolidinecarboxylic acid ethyl ester; L-Proline, 1-ethyl-, ethyl ester; Ethyl (S)-1-ethylpyrrolidine-2-carboxylate; (S)-(-)-1-Ethylpyrrolidine-2-carboxylic Acid Ethyl Ester; (-)-1-Ethyl-2-pyrrolidinecarboxylic Acid Ethyl Ester; (S)-1-Ethylpyrrolidine-2-carboxylic Acid Ethyl Ester; Ethyl L-1-ethylpyrrolidine-2-carboxylate
EINECS	213-340-8

Quality Control

Our (S)-(-)-1-Ethyl-2-Pyrrolidinecarboxylic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation [α]20/D	-30° to -40° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.