Description

Opipramol Dihydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) primarily used in the development and manufacturing of psychotropic medications. Its value lies in its critical role as the dihydrochloride salt form of Opipramol, offering enhanced stability and solubility for formulation. This compound is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and API producers focused on central nervous system (CNS) therapeutics.

Application

• Pharmaceutical API Synthesis: Primary use as an active ingredient in the manufacture of antidepressant and anxiolytic medications.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical testing.
• Biochemical Research: Used in preclinical studies to investigate pharmacological mechanisms related to tricyclic antidepressant activity and sigma receptor binding.
• Formulation Development: Employed in the development of various dosage forms, including tablets and capsules, due to its salt form properties.
• Process Chemistry: Acts as a key intermediate in advanced synthetic routes for producing related psychotropic compounds.

Basic Information

Product Name	Opipramol Dihydrochloride
CAS No.	909-39-7
Molecular Formula	C23H29N3O • 2HCl
Molecular Weight	444.41 g/mol
Synonyms	4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol dihydrochloride; Insidon; Pramolan; G-33040; Opipramol HCl; N-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-N'-(2-hydroxyethyl)piperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our Opipramol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and support regulatory submissions. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.