Description

(1S,2S)-(+)-N,N-Dimethylcyclohexane-1,2-diamine is a high-purity, chiral diamine compound characterized by its specific stereochemistry. This enantiomerically pure building block is critical for applications requiring precise molecular geometry and asymmetric induction. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of chiral catalysts, ligands, and active pharmaceutical ingredients (APIs).

Application

• Chiral Ligand & Catalyst Synthesis: A key precursor for creating sophisticated asymmetric catalysts used in enantioselective hydrogenation, transfer hydrogenation, and other stereospecific transformations.
• Pharmaceutical Intermediate: Serves as a vital chiral scaffold in the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Development: Employed in the synthesis of enantiomerically pure pesticides and herbicides, where the specific stereoisomer can significantly impact biological activity and environmental safety.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent to control stereochemistry in complex organic syntheses for fine chemicals and flavors & fragrances.
• Material Science Research: Investigated for the development of chiral polymers, metal-organic frameworks (MOFs), and other advanced materials with unique optical or catalytic properties.
• Academic & Process Chemistry: A valuable reagent for methodological studies in academic laboratories and for scaling up chiral processes in pilot plants.

Basic Information

Item	Detail
Product Name	(1S,2S)-(+)-N,N-Dimethylcyclohexane-1,2-diamine
CAS No.	894493-95-9
Molecular Formula	C8H18N2
Molecular Weight	142.24 g/mol
Synonyms	(1S,2S)-(+)-1,2-Diamino-N,N-dimethylcyclohexane; (1S,2S)-N,N-Dimethyl-1,2-cyclohexanediamine; (1S,2S)-DMCHD; (+)-trans-N,N-Dimethyl-1,2-diaminocyclohexane; (1S,2S)-DACH-NMe2; (S,S)-N,N-Dimethyl-1,2-diaminocyclohexane; (1S,2S)-N,N-Dimethylcyclohexane-1,2-diyldiamine; (1S,2S)-DACH-dimethyl
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-N,N-Dimethylcyclohexane-1,2-diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.