Description

2-(3,4-Difluorophenyl)-2-Oxoacetic Acid is a high-purity, fluorinated aromatic keto acid building block. This compound is valued for its role as a critical intermediate in the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. It is essential for research and development chemists and process engineers working on advanced drug candidates, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, where the difluorophenyl moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals, where fluorine substitution modifies physical properties.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying enzyme mechanisms and cellular processes.

Basic Information

Product Name	2-(3,4-Difluorophenyl)-2-Oxoacetic Acid
CAS No.	890097-94-6
Molecular Formula	C8H4F2O3
Molecular Weight	186.11 g/mol
Synonyms	2-Oxo-2-(3,4-difluorophenyl)acetic Acid; (3,4-Difluorophenyl)glyoxylic Acid; 3,4-Difluorophenylglyoxylic Acid; 3,4-Difluorobenzoylformic Acid; α-Keto-3,4-difluorophenylacetic Acid; 890097-94-6; 2-(3,4-Difluorophenyl)-2-oxoethanoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-(3,4-Difluorophenyl)-2-Oxoacetic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.