Description

4-(2-Amino-4-Fluorophenyl)Benzoic Acid is a high-purity, multifunctional aromatic compound featuring both a carboxylic acid and an amino group on a fluorinated biphenyl scaffold. This unique structure makes it a critical building block for advanced organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel small molecule therapeutics and high-value chemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials due to its rigid, functionalized biphenyl core.
• Fluorescent Probe and Dye Synthesis: Acts as a starting material for synthesizing specialized fluorophores and chromophores used in bio-imaging and diagnostics.

Basic Information

Product Name	4-(2-Amino-4-Fluorophenyl)Benzoic Acid
CAS No.	889950-33-8
Molecular Formula	C13H10FNO2
Molecular Weight	231.22 g/mol
Synonyms	2'-Amino-4'-fluorobiphenyl-4-carboxylic Acid; 4-(2-Amino-4-fluorophenyl)benzoic Acid; [1,1'-Biphenyl]-4-carboxylic acid, 2-amino-4'-fluoro-; 4-Carboxy-4'-fluoro-2-aminobiphenyl; 2-Amino-4'-fluorobiphenyl-4-carboxylic acid; Benzoic acid, 4-(2-amino-4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our production of 4-(2-Amino-4-Fluorophenyl)Benzoic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, supporting development under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.