Description

tert-Butyl 2-Bromo-4-Fluorobenzoate is a high-purity, synthetically valuable benzoate ester derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for introducing functionalized benzoate motifs into complex molecular architectures, enabling the development of novel active ingredients. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the reactivity of the bromo and fluoro substituents.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized monomers or additives for advanced polymers and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing tagged or modified molecules used as probes in biochemical and pharmacological research.

Basic Information

Product Name	tert-Butyl 2-Bromo-4-Fluorobenzoate
CAS No.	889858-12-2
Molecular Formula	C11H12BrFO2
Molecular Weight	275.12 g/mol
Synonyms	2-Bromo-4-fluorobenzoic acid tert-butyl ester; Benzoic acid, 2-bromo-4-fluoro-, 1,1-dimethylethyl ester; tert-Butyl 2-bromo-4-fluorobenzoate; 1,1-Dimethylethyl 2-bromo-4-fluorobenzoate; 2-Bromo-4-fluorobenzoic acid 1,1-dimethylethyl ester; t-Butyl 2-bromo-4-fluorobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromo-4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.