Description

3,6-Difluoro-2-Methoxybenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which introduces both fluorine atoms and a methoxy group to modulate the electronic and steric properties of target molecules. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro-methoxy motif can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Ligand Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs), leveraging its ability to fine-tune coordination geometry.
• Custom Chemical & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns requiring high-fidelity fluorinated intermediates.

Basic Information

Product Name	3,6-Difluoro-2-Methoxybenzoic Acid
CAS No.	887267-03-0
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	2-Methoxy-3,6-difluorobenzoic Acid; 3,6-Difluoro-2-methoxybenzoic Acid; Benzoic acid, 3,6-difluoro-2-methoxy-; 887267-03-0; 3,6-Difluoro-o-anisic Acid; 2-Methoxy-3,6-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 3,6-Difluoro-2-Methoxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.