Description

2,4,6-Trifluoro-3,5-Dimethylbenzoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of steric hindrance and electronic effects imparted by the fluorine and methyl substituents, which are critical for modulating the properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery, particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its ability to fine-tune electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise fluorination patterns.

Basic Information

Product Name	2,4,6-Trifluoro-3,5-Dimethylbenzoic Acid
CAS No.	886762-23-8
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3,5-Dimethyl-2,4,6-trifluorobenzoic Acid; 2,4,6-Trifluoro-3,5-dimethylbenzenecarboxylic Acid; Benzoic acid, 2,4,6-trifluoro-3,5-dimethyl-; 886762-23-8; TFDBA; 3,5-Dimethyl-2,4,6-trifluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluoro-3,5-Dimethylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.