Description

4-Chloro-3-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its unique combination of chloro and trifluoromethoxy substituents. This compound is essential for synthesizing advanced molecules where electronic modulation and enhanced lipophilicity are critical for performance. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas requiring fluorine-containing motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing specialized organic electronic materials, where its molecular structure contributes to desired electronic properties and molecular alignment.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for engineering polymers with specific thermal, chemical, or surface properties.
• Chemical Research & Development: A versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound library generation.
• Dye & Pigment Intermediate: Employed in the synthesis of complex dyes and pigments, contributing to color fastness and specific spectral characteristics.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethoxy)Benzoic Acid
CAS No.	886500-50-1
Molecular Formula	C8H4ClF3O3
Molecular Weight	240.56 g/mol
Synonyms	4-Chloro-3-(trifluoromethoxy)benzoic acid; 3-Trifluoromethoxy-4-chlorobenzoic acid; Benzoic acid, 4-chloro-3-(trifluoromethoxy)-; 886500-50-1; 4-Chloro-alpha,alpha,α-trifluoro-m-anisic acid; 4-Chloro-3-trifluoromethoxybenzoic acid; 4-Chloro-3-(trifluoromethoxy)benzoic acid (CAS 886500-50-1)
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-3-(Trifluoromethoxy)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.