Description

2,4-Difluoro-3-Methoxycinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for synthesizing novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing next-generation therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the fluorine atoms for improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with specific optical or electronic properties.
• Chemical Synthesis: Versatile intermediate for further functionalization via its carboxylic acid group, enabling the creation of amides, esters, and other derivatives for diverse R&D applications.
• Life Science Research: Used as a probe or standard in biochemical and pharmacological studies to investigate structure-activity relationships (SAR).

Basic Information

Product Name	2,4-Difluoro-3-Methoxycinnamic Acid
CAS No.	886499-22-5
Molecular Formula	C10H8F2O3
Molecular Weight	214.17 g/mol
Synonyms	(2E)-3-(2,4-Difluoro-3-methoxyphenyl)prop-2-enoic acid; 2,4-Difluoro-3-methoxycinnamic acid; 3-(2,4-Difluoro-3-methoxyphenyl)acrylic acid; trans-2,4-Difluoro-3-methoxycinnamic acid; (E)-3-(2,4-Difluoro-3-methoxyphenyl)acrylic acid; 2,4-Difluoro-3-methoxy-trans-cinnamic acid; 886499-22-5; Cinnamic acid, 2,4-difluoro-3-methoxy-
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Methoxycinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.