Description

4-Biphenyl-3',4'-Difluoro-Acetic Acid CAS NO 886363-36-6 is a high-purity, fluorinated biphenyl acetic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular architecture, which incorporates fluorine atoms and a carboxylic acid functional group, enabling precise modifications to enhance the properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atoms improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce fluorinated biphenyl groups into specialty polymers, enhancing thermal stability and chemical resistance.
• Chemical Research & Development: A versatile scaffold in medicinal and materials chemistry for structure-activity relationship (SAR) studies and the creation of compound libraries.
• Advanced Material Science: Employed in the development of organic semiconductors and other high-performance electronic materials.

Basic Information

Product Name	4-Biphenyl-3',4'-Difluoro-Acetic Acid
CAS No.	886363-36-6
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	3',4'-Difluoro[1,1'-biphenyl]-4-acetic Acid; [1,1'-Biphenyl]-4-acetic Acid, 3',4'-Difluoro-; 4-(3,4-Difluorophenyl)phenylacetic Acid; 3,4-Difluorobiphenyl-4-yl-acetic Acid; 4-Biphenyl-3',4'-difluoroacetic Acid; Biphenyl-3',4'-difluoro-acetic Acid; 886363-36-6 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 4-Biphenyl-3',4'-Difluoro-Acetic Acid is produced and tested under strict quality management protocols to ensure consistency and high purity suitable for research and commercial synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly closed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.