Description

n-Boc-β-Alanine-β-4'-Methoxyphenyl-n-Carboxyanhydride is a specialized N-carboxyanhydride (NCA) derivative, a crucial building block in the synthesis of complex peptides and polymers. This compound matters for its role in enabling controlled ring-opening polymerization (ROP) to create precisely engineered polypeptides with defined sequences and architectures. Pharmaceutical researchers and advanced material scientists need it for developing novel drug delivery systems, biodegradable materials, and functional biomimetic polymers.

Application

• Pharmaceutical Intermediate: Key monomer for the synthesis of peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Polymer Chemistry: Precursor for the controlled synthesis of poly(amino acid)s and polypeptide-based block copolymers via NCA ring-opening polymerization.
• Drug Delivery Systems: Building block for creating biodegradable, biocompatible polymeric carriers for controlled drug release.
• Biomaterials Engineering: Used in the development of hydrogels, scaffolds, and surface coatings with tailored biofunctional properties.
• Research & Development: Essential reagent in academic and industrial R&D for exploring new peptide architectures and smart materials.
• Conjugation Chemistry: Facilitates the site-specific attachment of peptides or functional groups to other molecules or surfaces.

Basic Information

Product Name	n-Boc-β-Alanine-β-4'-Methoxyphenyl-n-Carboxyanhydride
CAS No.	886362-61-4
Molecular Formula	C16H19NO6
Molecular Weight	321.33 g/mol
Synonyms	Boc-β-Ala-4-Methoxyphenyl NCA; tert-Butyloxycarbonyl-β-alanine-4-methoxyphenyl N-carboxyanhydride; (4-Methoxyphenyl) 3-[(tert-butoxycarbonyl)amino]propanoate-2,5-dione; N-(tert-Butoxycarbonyl)-β-alanine N-carboxyanhydride 4-methoxyphenyl ester; Boc-β-Ala-OMePhe NCA; N-Boc-3-aminopropanoic acid N-carboxyanhydride p-methoxyphenyl ester; NCA of Boc-β-Ala-4-MeO-Phe
EINECS	Contact for details

Quality Control

Our n-Boc-β-Alanine-β-4'-Methoxyphenyl-n-Carboxyanhydride is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive polymerization and pharmaceutical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.