Description

Methyl 4'-Nitro-3'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its biphenyl core with nitro and trifluoromethyl substituents. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific receptor sites. It is primarily required by R&D laboratories and production facilities in the pharmaceutical and agrochemical sectors for developing new drug candidates and high-performance crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug molecules, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new generation herbicides and pesticides with enhanced efficacy.
• Material Science: Used in the research and development of specialty polymers and liquid crystals due to its rigid biphenyl structure.
• Chemical Synthesis: Employed in organic synthesis for introducing the nitro and trifluoromethyl groups into complex molecular architectures.
• API Development: Integral in the process development and scale-up of target Active Pharmaceutical Ingredients (APIs).
• Life Science Research: Utilized in biochemical research as a tool compound for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	Methyl 4'-Nitro-3'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carboxylate
CAS No.	886361-47-3
Molecular Formula	C15H10F3NO4
Molecular Weight	325.24 g/mol
Synonyms	Methyl 4'-Nitro-3'-(trifluoromethyl)biphenyl-4-carboxylate; 4'-Nitro-3'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxylic Acid Methyl Ester; [1,1'-Biphenyl]-4-carboxylic Acid, 4'-Nitro-3'-(trifluoromethyl)-, Methyl Ester; Biphenyl-4-carboxylic Acid, 4'-Nitro-3'-(trifluoromethyl)-, Methyl Ester; Methyl 4'-Nitro-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4'-Nitro-3'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.