Description

3-[(2,3,4,5,6-Pentafluorophenoxy)Sulfonyl]Benzenecarboxylic Acid is a high-value, multi-functional chemical intermediate characterized by its unique perfluorinated aromatic ether and benzenesulfonyl carboxylic acid structure. This compound matters for its role as a sophisticated building block in the synthesis of advanced materials and active pharmaceutical ingredients, where its specific fluorine substitution pattern and reactive sites enable precise molecular design. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty polymer industries seeking to incorporate fluorinated motifs to enhance the metabolic stability, lipophilicity, or electronic properties of their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring enhanced bioavailability through fluorination.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pentafluorophenoxy group can contribute to improved weatherfastness and biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated components in electronic display materials, contributing to desired dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce sulfonyl and carboxylic acid functionalities into polymer backbones or side chains for creating ion-exchange membranes or high-performance engineering plastics.
• Cross-coupling Reagent Precursor: Can be transformed into active esters or other derivatives for use in peptide synthesis or palladium-catalyzed coupling reactions.
• Chemical Biology Probes: Utilized in the design of activity-based probes and fluorogenic substrates for studying enzyme mechanisms, leveraging its specific reactivity.

Basic Information

Product Name	3-[(2,3,4,5,6-Pentafluorophenoxy)Sulfonyl]Benzenecarboxylic Acid
CAS No.	886361-31-5
Molecular Formula	C13H5F5O5S
Molecular Weight	368.24 g/mol
Synonyms	3-[(Pentafluorophenoxy)sulfonyl]benzoic acid; Benzoic acid, 3-[(2,3,4,5,6-pentafluorophenoxy)sulfonyl]-; 3-(Pentafluorophenyloxysulfonyl)benzoic Acid; 3-Carboxybenzenesulfonic acid pentafluorophenyl ester; Pentafluorophenyl 3-carboxybenzenesulfonate
EINECS	Contact for details

Quality Control

Our 3-[(2,3,4,5,6-Pentafluorophenoxy)Sulfonyl]Benzenecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.