Description

6-Fluoro-1,2,3,4-Tetrahydro-Naphthalene-2-Carboxylic Acid is a high-purity fluorinated tetralin carboxylic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique combination of a rigid, partially saturated naphthalene scaffold with a strategically placed fluorine atom and a carboxylic acid functional group, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules in drug discovery and crop protection agent programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers or liquid crystals where the fluorinated tetralin structure imparts specific physical properties.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags or molecular probes to study biological processes.

Basic Information

Item	Detail
Product Name	6-Fluoro-1,2,3,4-Tetrahydro-Naphthalene-2-Carboxylic Acid
CAS No.	885269-59-0
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	6-Fluoro-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; 2-Naphthalenecarboxylic acid, 6-fluoro-1,2,3,4-tetrahydro-; 6-Fluoro-2-tetralincarboxylic acid; 6-Fluoro-3,4-dihydro-2-naphthoic acid; 6-Fluoro-1,2,3,4-tetrahydro-2-naphthoic acid; FTCA (abbreviation); 6-F-THNA-2-COOH
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1,2,3,4-Tetrahydro-Naphthalene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.