Description

6-Chloro-3-Fluoro-Pyridine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its unique halogenated pyridine structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Employed in the development of organic electronic materials, such as components for organic light-emitting diodes (OLEDs) or conductive polymers.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	6-Chloro-3-Fluoro-Pyridine-2-Carboxylic Acid
CAS No.	884494-76-2
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.54 g/mol
Synonyms	2-Carboxy-6-chloro-3-fluoropyridine; 3-Fluoro-6-chloropyridine-2-carboxylic acid; 6-Chloro-3-fluoropicolinic acid; 2-Pyridinecarboxylic acid, 6-chloro-3-fluoro-; 6-Chloro-3-fluoro-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-3-Fluoro-Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.