Description

Ethyl 4-Chloro-2,5-Difluorobenzoate is a high-purity fluorinated benzoate ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile molecular scaffold for constructing complex, fluorine-containing compounds essential for high-performance materials and active pharmaceutical ingredients. This product is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel molecules.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluorochlorophenyl moiety contributes to efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for fluorinated components in electronic display technologies and organic light-emitting diodes.
• Polymer & Material Science: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: Utilized in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce functionalized aryl groups.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Ethyl 4-Chloro-2,5-Difluorobenzoate
CAS No.	879093-03-5
Molecular Formula	C9H7ClF2O2
Molecular Weight	220.60 g/mol
Synonyms	Benzoic acid, 4-chloro-2,5-difluoro-, ethyl ester; Ethyl 4-chloro-2,5-difluorobenzoate; 4-Chloro-2,5-difluorobenzoic acid ethyl ester; 2,5-Difluoro-4-chlorobenzoic acid ethyl ester; Ethyl 4-chloro-2,5-difluorobenzoate (CAS 879093-03-5)
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-2,5-Difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.