Description

L-Phenylalanine-13C9,15N is a high-purity, isotopically labeled amino acid essential for advanced research and analytical applications. This compound, with CAS NO 878339-23-2, provides a critical internal standard for precise quantification in mass spectrometry, ensuring data accuracy and reproducibility. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and academic institutions engaged in metabolic pathway studies, proteomics, and stable isotope tracer experiments.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in LC-MS and GC-MS analyses for amino acid profiling in biological samples.
• Metabolic Flux Analysis (MFA): Serves as a stable isotope tracer to study phenylalanine metabolism and related pathways in cell cultures and organisms.
• Proteomics and Biomarker Research: Enables accurate protein quantification and turnover studies using stable isotope labeling techniques (SILAC).
• Pharmaceutical Development: Critical for pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug metabolism and amino acid incorporation.
• Clinical Diagnostics: Employed in developing assays for inborn errors of metabolism, such as phenylketonuria (PKU).
• Nutritional Science Research: Used to investigate protein synthesis, amino acid requirements, and dietary metabolism.

Basic Information

Item	Details
Product Name	L-Phenylalanine-13C9,15N
CAS No.	878339-23-2
Molecular Formula	13C915N C9H11NO2
Molecular Weight	~180.16 (based on labeled atoms)
Synonyms	(S)-2-Amino-3-(phenyl-13C6)propanoic-13C3,15N; L-Phe-13C9,15N; Phenylalanine-13C9,15N; F-13C9,15N; (S)-Phenylalanine-13C9,15N; Isotopically Labeled L-Phenylalanine; [U-13C9,15N]-L-Phenylalanine; Stable Isotope Labeled Phenylalanine
EINECS	Contact for details

Quality Control

Our L-Phenylalanine-13C9,15N is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, suitable for the most demanding analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and specific tests. We adhere to cGMP principles for research chemicals, and our quality commitment ensures reliable, reproducible, and traceable materials for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98% (Chemical Purity)
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 99 atom % 15N
Optical Rotation	[α]20/D: -33° to -37° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.