Description

Methyl 4-Fluoro-2-Iodo-6-Methylbenzoate is a high-purity, multi-functional halogenated benzoate ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular architecture, which incorporates fluorine and iodine atoms on an aromatic ring, making it a versatile building block for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the fluorine and iodine substituents can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis, such as cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers where halogenated aromatic units are required.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Methyl 4-Fluoro-2-Iodo-6-Methylbenzoate
CAS No.	877151-07-0
Molecular Formula	C9H8FIO2
Molecular Weight	294.06 g/mol
Synonyms	Methyl 4-fluoro-2-iodo-6-methylbenzoate; Benzoic acid, 4-fluoro-2-iodo-6-methyl-, methyl ester; 4-Fluoro-2-iodo-6-methylbenzoic acid methyl ester; 2-Iodo-4-fluoro-6-methylbenzoic acid methyl ester; Methyl 2-iodo-4-fluoro-6-methylbenzoate; 877151-07-0; Methyl 4-fluoro-2-iodo-6-methyl-benzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Fluoro-2-Iodo-6-Methylbenzoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets high-purity requirements suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.