Description

Boronic Acid, B-[3-Cyano-4-(2,2,2-Trifluoroethoxy)Phenyl]- is a high-purity, synthetically valuable organoboron compound. It serves as a critical building block in modern organic synthesis, particularly for the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients. Its unique structure, featuring both cyano and trifluoroethoxy substituents, makes it a key precursor for creating complex molecules with specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Employed in the creation of advanced organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations and academic laboratories exploring new synthetic pathways.

Basic Information

Product Name	Boronic Acid, B-[3-Cyano-4-(2,2,2-Trifluoroethoxy)Phenyl]-
CAS No.	876918-84-2
Molecular Formula	C10H7BF3NO3
Molecular Weight	257.97 g/mol
Synonyms	[3-Cyano-4-(2,2,2-trifluoroethoxy)phenyl]boronic acid; (3-Cyano-4-(2,2,2-trifluoroethoxy)phenyl)boronic acid; 4-(2,2,2-Trifluoroethoxy)-3-cyanophenylboronic acid; 3-Cyano-4-(2,2,2-trifluoroethoxy)benzeneboronic acid; Boronic acid, B-[3-cyano-4-(2,2,2-trifluoroethoxy)phenyl]-; 876918-84-2; B-[3-Cyano-4-(2,2,2-trifluoroethoxy)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our production of Boronic Acid, B-[3-Cyano-4-(2,2,2-Trifluoroethoxy)Phenyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be sealed immediately after use to minimize exposure to air and moisture. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.