Description

5-Amino-2,3-difluorobenzoic acid is a high-purity fluorinated benzoic acid derivative characterized by its amino and fluorine substituents, which confer unique reactivity and electronic properties. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex organic molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluoro and amino groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where fluorinated aromatic units are required to tune electronic properties and stability.
• Chemical Biology Probes: Utilized as a scaffold for designing fluorescent tags, enzyme inhibitors, and molecular probes due to its derivatizable carboxylic acid and amino functional groups.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Amino-2,3-Difluorobenzoic Acid
CAS No.	874838-32-1
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	2,3-Difluoro-5-aminobenzoic Acid; Benzoic acid, 5-amino-2,3-difluoro-; 5-Amino-2,3-difluorobenzoic acid; 2,3-Difluoro-5-aminobenzoic acid; 874838-32-1; 5-Amino-2,3-difluoro-benzoic acid; 5-Amino-2,3-difluorobenzoic acid, 97%
EINECS	Contact for details

Quality Control

Our 5-Amino-2,3-difluorobenzoic acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.