Description

2-Borono-5-Fluorobenzoic Acid is a high-purity, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, combining a boronic acid group with a fluorine substituent on an aromatic carboxylic acid, makes it an exceptionally versatile reagent for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require precise, reliable intermediates for cross-coupling reactions and the development of active ingredients. We supply this material with a focus on batch-to-batch consistency and technical support for your specific application needs.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes and inhibitors that target specific enzymes or biological pathways.
• Diagnostic Reagent Development: Utilized in creating components for biosensors and diagnostic assays due to its specific binding capabilities.
• Custom Synthesis & Contract Manufacturing: An important starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Borono-5-Fluorobenzoic Acid
CAS No.	874290-63-8
Molecular Formula	C7H6BFO4
Molecular Weight	183.93 g/mol
Synonyms	5-Fluoro-2-boronobenzoic Acid; 2-Carboxy-4-fluorophenylboronic Acid; (5-Fluoro-2-carboxyphenyl)boronic Acid; 4-Fluoro-2-boronobenzoic Acid; B-(5-Fluoro-2-carboxyphenyl)boronic Acid; 5-Fluoro-2-carboxyphenylboronic Acid; 2-Borono-5-fluorobenzoic acid; 874290-63-8
EINECS	Contact for details

Quality Control

Every batch of 2-Borono-5-Fluorobenzoic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Standard analytical techniques including HPLC, NMR (¹H, ¹³C, ¹⁹F, ¹¹B), and FTIR are employed to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.