Description

2-Carboxy-5-Fluorobenzeneboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the combination of a reactive boronic acid group and a carboxylic acid moiety, enabling versatile cross-coupling and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and advanced materials through Suzuki-Miyaura coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing complex biaryl structures in drug discovery and material science.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that benefit from fluorinated motifs.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors that target specific biological pathways.

Basic Information

Product Name	2-Carboxy-5-Fluorobenzeneboronic Acid
CAS No.	874290-62-7
Molecular Formula	C7H6BFO4
Molecular Weight	183.93 g/mol
Synonyms	5-Fluoro-2-carboxybenzeneboronic Acid; (2-Carboxy-5-fluorophenyl)boronic Acid; 5-Fluorophthalic Acid Boronic Acid; 2-Borono-5-fluorobenzoic Acid; 5-Fluoro-2-boronobenzoic Acid; 5-Fluoro-2-carboxyphenylboronic Acid; 2-Carboxy-5-fluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 2-Carboxy-5-Fluorobenzeneboronic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP standards where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.