Description

3-Fluoro-5-(Piperidin-1-Ylcarbonyl)Benzeneboronic Acid is a high-value boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both a boronic acid group and a fluorinated aromatic ring linked to a piperidine amide, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Employed in the creation of organic electronic materials and metal-organic frameworks (MOFs) due to its ability to form stable boron-based complexes.
• Chemical Biology Probe Development: Serves as a versatile handle for bioconjugation and the synthesis of activity-based probes for studying enzyme function.
• Process Chemistry & Scale-up: Provides a reliable and consistent building block for optimizing synthetic routes from laboratory to pilot plant scale.

Basic Information

Item	Details
Product Name	3-Fluoro-5-(Piperidin-1-Ylcarbonyl)Benzeneboronic Acid
CAS No.	874219-43-9
Molecular Formula	C13H17BFNO3
Molecular Weight	265.09 g/mol
Synonyms	[3-Fluoro-5-(1-Piperidinecarbonyl)phenyl]boronic Acid; 3-Fluoro-5-(piperidine-1-carbonyl)phenylboronic Acid; 3-Fluoro-5-(1-Piperidylcarbonyl)Benzeneboronic Acid; 5-Borono-3-fluoro-N-piperidin-1-ylbenzamide; 874219-43-9; 3-Fluoro-5-(piperidin-1-ylcarbonyl)benzeneboronic acid pinacol ester (common precursor); 3-Fluoro-5-(N-piperidinyl)carboxamidophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Piperidin-1-Ylcarbonyl)Benzeneboronic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.