Description

3-(Benzylcarbamoyl)-5-Fluorobenzeneboronic Acid is a high-purity, advanced pharmaceutical intermediate and a key building block in modern synthetic chemistry. This compound is valued for its role as a versatile boronic acid derivative, essential for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated biaryl motifs for oncology, CNS, and antiviral therapies.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a key electrophilic partner for palladium-catalyzed carbon-carbon bond formation, enabling the construction of complex, drug-like molecules.
• Agrochemical Research: Used in the discovery and development of new generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, liquid crystals, and fluorescent materials for electronic displays and devices.
• Chemical Biology & Probe Development: Utilized for creating molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(Benzylcarbamoyl)-5-Fluorobenzeneboronic Acid
CAS No.	874219-41-7
Molecular Formula	C14H13BFNO3
Molecular Weight	273.07 g/mol
Synonyms	5-Fluoro-3-[(phenylmethyl)carbamoyl]benzeneboronic Acid; [3-(Benzylcarbamoyl)-5-fluorophenyl]boronic Acid; 3-Carbamoyl-5-fluorobenzeneboronic Acid N-benzyl; B-[3-[(Benzylamino)carbonyl]-5-fluorophenyl]boronic Acid; 3-Benzylaminocarbonyl-5-fluorobenzeneboronic Acid; 3-(N-Benzylcarbamoyl)-5-fluorophenylboronic Acid; 874219-41-7; 5-Fluoro-N-benzyl-3-boronobenzamide
EINECS	Contact for details

Quality Control

Our 3-(Benzylcarbamoyl)-5-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.