Description

3-Fluoro-5-(Morpholin-4-Ylcarbonyl)Benzeneboronic Acid is a high-value boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both a boronic acid group and a fluorinated aromatic ring linked to a morpholine carboxamide, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its consistent quality and purity are paramount for ensuring high-yield, reproducible reactions in demanding R&D and scale-up environments.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require fluorinated aromatic components.
• Material Science: Serves as a monomer or building block for creating advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and inhibitors targeting specific enzymes.
• Catalyst Ligand Synthesis: Utilized to prepare sophisticated ligands for transition metal catalysis.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	3-Fluoro-5-(Morpholin-4-Ylcarbonyl)Benzeneboronic Acid
CAS No.	874219-40-6
Molecular Formula	C11H13BFNO4
Molecular Weight	265.04 g/mol
Synonyms	[3-Fluoro-5-(morpholine-4-carbonyl)phenyl]boronic acid; 3-Fluoro-5-(4-morpholinylcarbonyl)benzeneboronic acid; 3-Fluoro-5-morpholin-4-ylcarbonylbenzeneboronic acid; 5-Borono-3-fluoro-N-morpholinobenzamide; 874219-40-6; B-3-Fluoro-5-(morpholin-4-ylcarbonyl)phenylboronic acid; 3-Fluoro-5-(morpholine-4-carbonyl)benzeneboronic acid pinacol ester (common precursor).
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Morpholin-4-Ylcarbonyl)Benzeneboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.