Description

3-Ethoxycarbonyl-4-Fluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated biaryl compounds, which are prevalent in drug discovery for metabolic stability and bioavailability enhancement.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate fluorinated aromatic systems for improved efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors, where fluorinated units can tune electronic properties.
• Chemical Biology Probes: Useful for the synthesis of fluorinated probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	3-Ethoxycarbonyl-4-Fluorophenylboronic Acid
CAS No.	874219-36-0
Molecular Formula	C9H10BFO4
Molecular Weight	211.99 g/mol
Synonyms	(3-(Ethoxycarbonyl)-4-fluorophenyl)boronic acid; 4-Fluoro-3-(ethoxycarbonyl)benzeneboronic acid; 3-Carbethoxy-4-fluorobenzeneboronic acid; Ethyl 4-fluoro-3-boronobenzoate; Boronic acid, B-[3-(ethoxycarbonyl)-4-fluorophenyl]-; 874219-36-0; 3-Ethoxycarbonyl-4-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Ethoxycarbonyl-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.