Description

3-(Aminocarbonyl)-4-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling precise cross-coupling reactions essential for constructing complex molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs or sensors.
• Chemical Biology & Proteomics: Employed in the synthesis of chemical probes and affinity ligands for studying protein function and enzyme activity.
• Ligand Development for Catalysis: Acts as a starting material for synthesizing novel bidentate or tridentate ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated boronic acid derivatives.

Basic Information

Product Name	3-(Aminocarbonyl)-4-Fluorobenzeneboronic Acid
CAS No.	874219-34-8
Molecular Formula	C7H7BFNO3
Molecular Weight	182.95 g/mol
Synonyms	4-Fluoro-3-carbamoylbenzeneboronic Acid; 3-Carbamoyl-4-fluorobenzeneboronic Acid; (3-Carbamoyl-4-fluorophenyl)boronic Acid; 4-Fluoro-3-aminocarbonylbenzeneboronic Acid; B-(3-Carbamoyl-4-fluorophenyl)boronic Acid; 874219-34-8; 3-Aminocarbonyl-4-fluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-(Aminocarbonyl)-4-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.