Description

4-Fluoro-3-(Phenylcarbamoyl)Benzeneboronic Acid is a high-value boronic acid derivative and a versatile building block in modern synthetic chemistry. Its core value lies in its dual functionality, serving as a key intermediate in the synthesis of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers. Its specific structure makes it critical for projects requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its boronic acid group for efficient coupling reactions.
• Material Science Research: Serves as a monomer or precursor in the development of advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Suzuki-Miyaura Cross-Coupling: Acts as a key boronic acid partner in palladium-catalyzed cross-coupling reactions to form biaryl and other carbon-carbon bonds with high efficiency and selectivity.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and affinity ligands for studying biological processes and protein interactions.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated ligands for asymmetric catalysis and other transition metal-catalyzed transformations.

Basic Information

Item	Detail
Product Name	4-Fluoro-3-(Phenylcarbamoyl)Benzeneboronic Acid
CAS No.	874219-33-7
Molecular Formula	C13H11BFNO3
Molecular Weight	259.04 g/mol
Synonyms	[3-(Phenylcarbamoyl)-4-fluorophenyl]boronic acid; 4-Fluoro-N-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (Pinacol ester precursor); 3-Carbamoyl-4-fluorobenzeneboronic acid (Phenyl derivative); B-[3-(Phenylaminocarbonyl)-4-fluorophenyl]boronic acid; 4-Fluoro-3-benzamidobenzeneboronic acid; CAS 874219-33-7
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Phenylcarbamoyl)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.